Seems lots of people read posts about traveling certain highways but don't respond so much. I haven't traveled the Miami area myself but wouldn't think it would be much worse than Atlanta. I have a Ram 2500 and pull a 35 ft travel trailer so we are probably about the same length. I just plan ahead for turns and work my way into the exit lane in advance. We also plan to travel high congested areas outside the go to or return home from work hours.
I try to stay away from I 95
as much as I can. Just don't like it. Looks like you are in the Wilmington area just east of I95 so not much choice of route to travel.
Hope you have a fun, safe, and enjoyable trip.