None of the trucks mentioned here are without problems.
I have an 06 F-350 that has been a good truck and the only problem I have had was the injector pump. It was under warranty at the time and I have not had any problems with it since. I also have an 05 F-550 with the same motor and it has injector problems (stiction) but not that bad to fix either.
A few company's I work for have bought Dodges and have had problems ranging from poor quality body panels and interior parts coming loose/off.
Both companies have had to replace the engines from blown head gaskets. These are year models 02-09.
All of the Dodge trucks (3/4 ton and above) gas or diesel have IMO, worthless transmissions and have been replaced at least 3 times per truck (5 trucks in total).
GM is not without it's problems either, but I have not owned one so I can not comment on that. We do have a few of their gassers and they are for the most part problem free as well as the Ford gassers.
Most of the newer trucks have better components now then before and all have their belivers and ney sayers so you will need to do your homework and research.
Trucks here in Colorado do get driven harder just because of the mountains and I find alot of failures happen because people try to do to much aftermarket upgrades and just plain take their trucks beyond what they are capable of.
I am not slaming these makers for anything other than what I see on a daily basis and no one is without blame.
I do however belive Dodge should have given it's owners a better tranny!!
It really is a pile of junk. JMO