I like to drive the "US Highways" instead of the Interstates and haven't had any problems. Many are four lane divided for many miles.
Have taken US 82 from Tifton, GA to Wichita Falls, TX
US 287 from Fort Worth, TX to Laramie, WY
US 84 from Santa Fe, NM to near Hattiesburg, MS then US 98 to Mobile, AL
US 99 and US 101 North/South in CA
2011 Rockwood Windjammer 2102W
2008 Ram Laramie 3500 Megacab 4x4 Cummins 6.7L Turbo Diesel
(the max loaded 2006 F150 5.4L V8 would only go 55 MPH Westbound on I-80 in Wyoming)