As bad as I hate to say it, the answer is yes, but...
If all the appliances run back to the distribution panel on separate circuits it'll be easy. Just buy a 50 amp distribution center and wire approx half the loads to one phase and half to the other, replace the power cable with a 50 amp one and you're done. Unless you have a genset and a transfer switch. I won't go into that yet because you didn't say that was an issue.
Here is a list of power hungry devices that I can think of off the top of my head. You may have more.
12V Converter (55 amp 12 volt)
50 amps should run all these. I figured them at about 45 amps with all running, so theoretically you could run everything on one leg of the 50 amp hookup. You might not want to do this but it's possible. Most of the times they run one A/C and the washer/dryer on one phase and the rest of the stuff on the other.
Check with these folks on what you need to do. Best Converter
They are a great resource.