First, If you have a transmission idiot gauge on your dash, then it gets it's info from your PCM and then yes you should be able to use the xgauge feature to decipher the codes.
Second, forget the transmission temp gauge on your F series pickup. You won't get the needle to budge until your true temp is around 230 degrees. By that time you have to back 'er down or risk trans failure at around 250.
Third, are you gas or diesel? If diesel, I suggest perusing the 'Ford Truck Enthusiast' forum for specific 6.7L information. There are plenty of functions readily available on xgauge for diesels. I'm not sure about gas burners although from the limited threads I've read in the Super Duty section, the owners do use ScanGauge II as an effective basic code checker and engine monitor system.
2010 Cedar Creek 5th Wheel 34SATS "The Beast"
2006 Ford F350 Lariat 6.0L Diesel
2003 Harley Heritage Softail "Hogzilla"
1988 Harley Softail Custom "The Fireman"
1986 Marriage to "Wifey" (patience of a saint)