Mike and Rose
Our Rts last spring from western MA...I91, I84, I81 ( stayed at Flying J Carlisle, PA), back on I81(exit 300) to I66 to Rt 17(divided highway) to I95 at Fredericksburg, VA (We did a side trip to Colonial Williamsburg, VA), back on I95 (stayed at Lazy Acres Campground Fayetteville, NC), then I95 to FL. stayed with friends.
This route brought us away from the "major cities". It's not that much longer and I95 south of DC is a decent drive.
Do you use Good Sam Club-Road Trip Planner...it helps with routes and campgrounds and Flying J locations.
Hope this helps.
Happy
Trails