I am the one who takes care of the TT around here and this is what I have been doing:
Before first outing of the year, every square inch of the interior is washed (yes ceiling included) and vacuumed; our TT sits in a dusty storage yard all winter with the vent open so it needs it.
Exterior and roof is washed (sides waxed), windows done also.
During trips, floors wiped down and swept several times a day; spot cleaning as needed for sinks, toilet, countertops. For getting those annoying crumbs off the dinette cushions I use a fabric lint roller which works perfectly!
Awning gets wiped down prior to roll-up when we leave the CG.
After trips pretty much everything gets washed/wiped down again making sure no crumbs are in cabinets etc, because I dont want anything to attract critters while TT is at the storage place between outings. I vacuum the mattresses, dinette cushions and pay special attention to the cracks and crevices near where my dog sleeps because fleas and such love hiding in those spots.
I wash the bugs off the front, clean windows and only wash the other 3 sides if needed. I don't do the roof.
I guess it also all depends on the size of your TT; mine is small so it does not take long. Those with big 5th wheels etc is another story altogether.