It depends totally on your age, physical condition and tolerance. I'm 73, have some arthritis and get cramps in my thighs after about 3 hours. Our daily limit was about 180 - 220 miles. DW, being only 4' 10" tall, couldn't drive the rig at all, due to limited steering column angle adjustment and no telescoping column or pedal cluster adjustment.
In retrospect, we probably shouldn't have gone into RVing, but we enjoyed the three years we did it.
Frank and Eileen
No longer RVers or FR owners