Yes, I do. When traveling more than a couple of hours from home, I carry an extra spare. Call it overkill or whatever you want, but twice now I've had camping buddies blow out two tires within a few miles of each other, and one blow out two at the same time. Also, my rig is so heavy that if I lose one tire, even with a TPMS, by the time I get stopped, the good tire is going to be well over loaded which can cause significant damage to it. I have a rule that if one tire on the rig blows out, change both at the earliest convenience.
2012 Sandpiper 365SAQ weighing @ 15k, Onan, 2nd air, slide toppers, TST
2013 F350 6.7L Lariat 4x4 CC DRW,Viair 1007, Ride-Rites, Edge CTS, B&W
2001 Chevy 3500CC DRW 4x4, 8.1L, 4.10 gears w/ Detroit TrueTrac
2001 Ford Excursion Limited 4x4 7.3L,V/B Spring Mod, ProComps, Hellwig Swaybar, & other 'Necessities'