Yes, I use bead balancing on my F550 with 19.5 inch wheels. They work great. Since they dynamically balance, having some mud or stones in the tread makes no difference the tires run balanced.
I got them because the truck had a slight imbalance at 80 km/hr (50 mph) which was really annoying. The Ford dealer said that was normal and could not do balancing there. I'm very please with Counter Balance beads.
2004 Ford F550 6l Lariat SuperCrew, Fontaine Bed,
Link Systems Air Ride
2011 Sterling 32RL with Michelin XPS tires