I own a 2001 Mirada. A lot has changed in 11 years.
As for the Ford F53 chassis, from the postings I see on another board, it looks like a good chassis. Your V10 has 362 hp, mine has 310 hp. You shouldn't have any problems with the engine or weight. Remember, its a truck, not a car. :-)
The one thing that seems to crop up on the newer F53 chassis is the rear torsion bar (sway bar) bushings, mounts, and bolts.
There are reports of the bolts falling out; climb under there and check this.
ALSO - for better handling, there is a small modification to the sway bars that can be done that vastly improves the handling, its called the "Cheap Handling Fix" (CHF for short). Basically all you need to do is change position of the drag links on the torsion bars. The links are bolted to the front holes on the torsion bars from the factory. The fix is to move the links to the rear set of holes on the torsion bars.
There is also reports of goofy transmission shift scheduling. i.e. downshifting two gears at a bad time, etc. It appears that the "5 Star tune" can correct this by reprogramming tranny shifting point. (This doesn't effect my 2001)
As for the interior - yours would be vastly different than mine. Mine is a "lower end of the middle" as far as quality and features.
One thing to look at as far as the coach would be the Frig access panel on the outside to make sure it has a water lip on the bottom of the frame (DO THIS REGARDLESS OF ANY MH YOU BUY) .
Read this article and you'll see exactly what I'm talking about
Fixing Frig exterior access panel door leaks | 2001 Coachmen Mirada 300QB
Repairing water damage caused by frig door:
Repairing Delamination and water damage | 2001 Coachmen Mirada 300QB