We bought a 35DB last November, and we couldn't be happier. We have 3 boys, and it fits us perfectly. The driving experience is great - we're about 1300 miles in to a 9000 mile trip over the summer, and it's been handling the mountains with ease - passing semis on the ascents, and, with the exhaust brake system and the auto-downshift when in tow/haul mode, I don't have to use the brakes at all on the 8% down grades - and this is all while towing the car.
For handling wind, I've been super impressed - the Isata 5 deals with cross winds *so* much better than the Class A we rented last summer - I'm not fighting winds at all. I still have to steer in to a strong wind, but it doesn't float all over the road, and there's almost no sway.
I've gotten admirers pretty much every day of the trip so far, many just completely blown away. Lot's of people super-surprised to see a coach on the Ram chassis, and very intrigued.
One of the other things that is just amazing is bclemens and zgipson here on the forum - I have never seen the level of customer orientation and service that these two provide, and they take customer input very seriously, making changes on the production line and quality control process based on feedback from this forum. They also jump in any time someone has a problem (either in the field or with a dealer), and help them get the issue resolved.
To sum up - do it, you'll love your Isata 5!