This is what i learned over at the Sprinter-Forum.
Don't idle long
No short trips
No Bio-fuel if you can help it
Use engine oil specified for vehicle
Drive it like you stole it, diesels like to run hot
Most of all problems are in the emission system, you ever hear of swirl valves? yes crazy components like that exist in your Sprinter, this is just one of the items to get gummed up if you load the engine up with soot.
I put 30K, prior owner put 20K, now has 50K on the Sprinter so far with no issues cause I follow the above recommendations.
2010 Coachmen Prism M240
(2008 Freightliner 3500 chassis)