Leave them on unless you plan on opening windows for ventilation. An alternative might be to only take one off to create a draft if you plan to open your vents or use your Fantastic Fan...
Happy Camping! ///// Richard D.
2006 4x4 Ford 250 SD / 2007 Flagstaff 827 FLS
One very patient wife and one furry child who travels with us. Forty-two years of trailering and camping, and I still have a blast.