Depending on your route. If you go north on 55 out of Memphis, you could see Ozark National Scenic Riverways. (I think someone mentioned this earlier.) If you go to St. Louis, the Arch, St. Louis Cardinals, (Fan or no this is a first class organization and stadium) St. Louis Zoo (Which is free admission) and St. Louis is also a microbrew haven....no you dont have to drink to excess, they all serve good food also....and finally in Missouri the Branson/Lakes area.
Out west I liked the Grand Canyon, Four Corners, (not really sure why) and Mesa Verde.
Jeff and Dana McCreary
2004 F-250 SuperCrew Lariat 6.0 Diesel
2003 Cardinal 312 BH