Well that all depends. What do you consider a weekend? Do you start Friday after work so you need Friday night and Saturday night? Do you leave Saturday morning so you only need one night? How far you normally travel easily? If we have all that then we can probably help.
Turkey Run if you like the outdoors and hiking plus great roads to ride on over there, Kickapoo state park is nice. Anywhere around Lake Monroe in Brown county IN. Hauking Hills in ohio, just to name a few we like to visit. I am also from central IL.