Adding bleach to the hose, as mentioned, is the most common way.
A friend of mine made a way to ingest the bleach into the system using a garden hose chemical sprayer. They added a short garden hose hose to the outlet end of the sprayer, (which was then hooked to the city/fill port on the side of the rig) added bleach to the container, connected a garden hose to the inlet side of the sprayer and viola!, as the water entered the fresh tank passing through the sprayer, so did the bleach.
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