I would be more concerned if the hubs on either side were 1/4" different in space front to back. The axles and brake drums may seem to be 1/4" wider due to the bearings and races not being as tight on one instead of the other.
2017 Forest River Surveyor 247BHDS...
...Tugged by a 2016 F250 XLT FX4 SuperCrew, Shortbed 6.2L, 4wd, 3.73...
...Joined with a Husky Centerline TS 800-1200lbs WDH