On the electric side, you want to have batteries of the same chemistry, age and capacity. No isolator needed. For best balance of the two, keep your current negative cable on the bottom battery and move the positives to the added battery (diagonal connection). You're not changing loads, so no wire change needed.
On the physical side, the box design would need access and ventilation to each battery. Stacked you would need enough strength to counter tipping when braking. I had added one to my trailer next to the original on the tongue in its own box. Later I changed to one big box that had room for both plus some other additions.
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2019 Palomino Solaire 147X
2013 Ford F150
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