That highway will beat any trailer, with any axle type, if driving "lower 48 freeway speeds".
My Torflex axles have held up well since 2017 on forest service roads but 35 mph is the normal speed on the "washboard" portions.
I worry less about my suspension on rough roads and more about the damage to the inside when roads are rough. Bottoms falling out of drawers, rods coming loose in closets with hanging clothes, etc.
Another casualty of driving fast on those highways is rock damage to everything on the front of your tow vehicle and trailer. Rocks tossed up by passing traffic hit far harder the faster you go. Headlights, windshields, trailer front, and even A/C condensers are common casualties.
I traveled for work extensively in AK between 1972 and 1985 and every once in a while I was able to rent a car with an unbroken windshield.